Protein Purification
MilliporeSigma™ Calbiochem™ CCR2 Antagonist
The CCR2 Antagonist, also referenced under CAS 445479-97-0, controls the biological activity of CCR2.
MilliporeSigma™ Calbiochem™ GPR40 Agonist
The GPR40 Agonist, also referenced under CAS 885101-89-3, controls the biological activity of GPR40. This small molecule/inhibitor is primarily used for Cell Signaling applications.
MilliporeSigma™ Calbiochem™ Indirubin-3'-monoxime-5-sulphonic Acid
A potent, reversible, and selective inhibitor of Cdk1 (IC50 = 5 nM) and Cdk5 (IC50 = 7 nM) and glycogen synthase kinase-3β (GSK-3β; IC50 = 80 nM).
MilliporeSigma™ Calbiochem™ AG 18
A broad-spectrum protein tyrosine kinase inhibitor.
MilliporeSigma™ Calbiochem™ GM 6001
GM 6001, CAS 142880-36-2, is a potent, cell-permeable, broad-spectrum inhibitor of matrix metalloproteinases.
MilliporeSigma™ Calbiochem™ Histone Acetyltransferase Inhibitor II
The Histone Acetyltransferase Inhibitor II, also referenced under CAS 932749-62-7, controls the biological activity of Histone Acetyltransferase. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ RHC-80267
Selective inhibitor of DAG lipase activity in canine platelets (IC50 = 4 nM) and in a variety of mammalian cells.
MilliporeSigma™ Calbiochem™ IRE1 Inhibitor II
The IRE1 Inhibitor II controls the biological activity of IRE1.
MilliporeSigma™ Calbiochem™ Guanosine 3',5'-cyclic Monophosphorothioate, 8-(4-Chlorophenylthio)-, Rp-Isomer, Triethylammonium Salt
A potent, cell-permeable, and metabolically-stable inhibitor of protein kinase G Iα, Iβ, and type II.
MilliporeSigma™ Calbiochem™ AG 1478
A cell-permeable, reversible, ATP-competitive, highly potent and selective inhibitor of epidermal growth factor receptor kinase versus HER2-neu and platelet-derived growth factor receptor kinase.
MilliporeSigma™ Calbiochem™ SIRT1/2/3 pan Inhibitor
A thienopyrimidinylcarboxamide that acts as a highly potent, reversible pan sirtuin (SIRT) inhibitor (IC50 = 15, 10, and 33nM for SIRT1, 2, and 3, respective
MilliporeSigma™ Calbiochem™ Eg5 Inhibitor IV, VS-83
The Eg5 Inhibitor IV, VS-83, also referenced under CAS 909250-29-9, controls the biological activity of Eg5. This small molecule/inhibitor is primarily used for Cell Structure applications.
MilliporeSigma™ Calbiochem™ Merbarone
A cell-permeable anticancer drug that inhibits the catalytic activity of topoisomerase II (topo II) without damaging DNA or stabilizing DNA-topo II cleavable complexes.
MilliporeSigma™ Calbiochem™ TNF-α Inhibitor
The TNF-α Inhibitor, also referenced under CAS 1049741-03-8, controls the biological activity of TNF-α.